‘Perio plus’ proves beneficial in viral load reduction

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  Posted by: Dental Design      3rd September 2021

A new study[i] has found that ‘Perio plus regenerate’ mouthwash reduces SARS-CoV-2 viral load in saliva.

The multicentre, double-blind study demonstrated that a single rinse of ß-cyclodextrin-citrox mouthwash (‘Perio plus regenerate’) significantly decreased the risk of SARS-CoV-2 contamination through saliva in patients with no to mild symptoms of COVID-19 4 hours after initial dose.

There was a significant difference in viral load when comparing before and after mouth rinsing between the ‘Perio plus regenerate’ mouthwash and placebo group. Participants with the ß-cyclodextrin-citrox mouthwash also experienced a greater reduction in viral load over seven days compared to the placebo group.

These initial results suggest that ‘Perio plus regenerate’ could provide an effective additional barrier to viral transmission for patients pre- and post-treatment.

For more details about the ‘Perio plus’ range of mouth rinses, toothpaste and gel – which feature a unique formulation containing Citrox, a natural bioflavonoid extracted from bitter oranges –visit the website today.


For more information please call 01480 862084, email info@curaprox.co.uk or visit www.perioplus.com/uk


[i] Carrouel F, Valette M, Gadea E, Esparcieux A, Illes G, Langlois ME, Perrier H, Dussart C, Tramini P, Ribaud M, Bouscambert-Duchamp M, Bourgeois D. Use of an antiviral mouthwash as a barrier measure in the sars-cov-2 transmission in adults with asymptompatic to mild COVID-19: a multicentre, randomized, double-blind controlled trial. Clinical Microbiology and Infection. May 2012. https://doi.org/10.1016/j.cmi.2021.05.028


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